Severe Aplastic Anaemia (SAA) is a rare Elbow Pads benign disease but carries a high-mortality rate unless treated in a specialised centre.Overwhelming laboratory and clinical evidence points to an autoimmune pathogenesis; although, the aetiology remains obscure in the majority of cases.The differential diagnosis in older patients is problematical and a diagnosis of hypoplastic myelodysplasia Holders remains difficult.
This review points out the difficulty in diagnosis without a specific test.Future research needs to define a specific diagnostic test and refine therapeutic interventions.